| Accession | TIGR00577 |
| Name | fpg |
| Function | formamidopyrimidine-DNA glycosylase |
| Gene Symbol | mutM |
| Trusted Cutoff | 203.30 |
| Domain Trusted Cutoff | 203.30 |
| Noise Cutoff | 105.10 |
| Domain Noise Cutoff | 105.10 |
| Isology Type | equivalog |
| EC Number | 3.2.2.23 |
| HMM Length | 276 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0005737: cytoplasm cellular_component |
| | GO:0006281: DNA repair biological_process |
| | GO:0008534: oxidized purine base lesion DNA N-glycosylase activity molecular_function |
| Author | Loftus BJ, Eisen JA |
| Entry Date | Oct 19 1999 6:19PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | All proteins in the FPG family with known functions are FAPY-DNA glycosylases that function in base excision repair. Homologous to endonuclease VIII (nei). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). |
| References | GA hmmsearch
GA hmmsearch
GA hmmsearch
DR EGAD; 8852;
DR SWISSPROT; P05523;
RM 88082692;
DR HAMAP; MF_00103; 329 of 333 |