HMM Summary Page: TIGR00630

Functionexcinuclease ABC subunit A
Gene SymboluvrA
Trusted Cutoff729.80
Domain Trusted Cutoff729.80
Noise Cutoff289.80
Domain Noise Cutoff289.80
Isology Typeequivalog
EC Number3.1.25.-
HMM Length924
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0006289: nucleotide-excision repair biological_process
GO:0009380: excinuclease repair complex cellular_component
GO:0009381: excinuclease ABC activity molecular_function
AuthorLoftus BJ, Eisen JA
Entry DateOct 20 1999 11:57AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesGA hmmsearch DR EGAD; 6128; DR HAMAP; MF_00205; 90 of 94
Genome PropertyGenProp0114: nucleotide excision repair (HMM)