HMM Summary Page: TIGR00694

Functionhydroxyethylthiazole kinase
Gene SymbolthiM
Trusted Cutoff256.40
Domain Trusted Cutoff256.40
Noise Cutoff110.90
Domain Noise Cutoff110.90
Isology Typeequivalog_domain
EC Number2.7.1.50
HMM Length249
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryThiamine
Gene Ontology TermGO:0004417: hydroxyethylthiazole kinase activity molecular_function
GO:0009228: thiamine biosynthetic process biological_process
AuthorLoftus BJ, Haft DH
Entry DateJan 13 2000 2:41PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the hydoxyethylthiazole kinase, ThiM, of a number of bacteria, and C-terminal domains of bifunctional thiamine biosynthesis proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe, in which the N-terminal domain corresponds to the bacterial thiamine-phosphate pyrophosphorylase (EC, ThiE.
ReferencesAL clustalw DR SWISSPROT; P76423 DR ECOCYC; EG14069; thiM DR EXPERIMENTAL; EGAD|90780|EC2104; Escherichia coli DR EXPERIMENTAL; EGAD|56426|YPL214C; Saccharomyces cerevisiae RN [1] RM 93352421 RN [2] RM 89255088 DR HAMAP; MF_00228; 110 of 142