|Function||DNA-binding protein, Tfx family|
|Domain Trusted Cutoff||60.25|
|Domain Noise Cutoff||45.40|
|Mainrole Category||Regulatory functions|
|Subrole Category||DNA interactions|
|Entry Date||Feb 1 2000 10:52AM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||PSI-BLAST starting with one member of this family converges with significant hits only to other members of the family, which is restricted to the Archaea. Homology is strongest in the helix-turn-helix-containing N-terminal region.
Tfx from Methanobacterium thermoautotrophicum is associated with the operon for molybdenum formyl-methanofuran dehydrogenase and binds a DNA sequence near its promoter.|
DR SWISSPROT; P56811
RT The DNA binding protein Tfx from Methanobacterium thermoautotrophicum: structure, DNA binding properties and transcriptional regulation.
RA Hochheimer A, Hedderich R, Thauer RK
RL Mol Microbiol 1999 Jan;31(2):641-50
DR HAMAP; MF_00620; 10 of 10|
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