HMM Summary Page: TIGR00730

FunctionTIGR00730 family protein
Trusted Cutoff96.35
Domain Trusted Cutoff96.35
Noise Cutoff63.80
Domain Noise Cutoff63.80
Isology Typehypoth_equivalog
HMM Length178
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorHaft DH
Entry DateFeb 22 2000 11:31AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this HMM show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions.
ReferencesRN [1] RM PMID:15459330 RT Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8. RA Kukimoto-Niino M, Murayama K, Kato-Murayama M, Idaka M, Bessho Y, Tatsuguchi A, Ushikoshi-Nakayama R, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S RL Protein Sci. 2004 Nov;13(11):3038-42. Epub 2004 Sep 30.