HMM Summary Page: TIGR00756

Functionpentatricopeptide repeat domain
Trusted Cutoff15.50
Domain Trusted Cutoff15.50
Noise Cutoff13.40
Domain Noise Cutoff13.40
Isology Typerepeat
HMM Length35
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes a domain called the PPR motif, or pentatricopeptide repeat. Its consensus sequence is 35 positions long and typically is found in four or more tandem copies. This family is strongly represented in plant proteins, particularly those sorted to chloroplasts or mitochondria. The pfam hmm PF01535, domain of unknown function DUF17, consists of 6 copies of this repeat. This family has a similar consensus to the TPR domain (tetratricopeptide), pfam PF00515, a 33-residue repeat. It is predicted to form a pair of antiparallel helices similar to that of TPR.
ReferencesA2 hmmalign AL hmmalign RM 20130690 RT The PPR motif - a TPR-related motif prevalent in plant organellar proteins. RA Small ID, Peeters I RL Trends Biochem Sci 2000 Feb;25(2):45-7