HMM Summary Page: TIGR00767

Functiontranscription termination factor Rho
Gene Symbolrho
Trusted Cutoff509.45
Domain Trusted Cutoff509.45
Noise Cutoff313.20
Domain Noise Cutoff313.20
Isology Typeequivalog
EC Number3.6.4.-
HMM Length415
Mainrole CategoryTranscription
Subrole CategoryTranscription factors
Gene Ontology TermGO:0003715: transcription termination factor activity molecular_function
GO:0004386: helicase activity molecular_function
GO:0006353: transcription termination, DNA-dependent biological_process
GO:0008186: RNA-dependent ATPase activity molecular_function
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis RNA helicase, the transcription termination factor Rho, occurs in nearly all bacteria but is missing from the Cyanobacteria, the Mollicutes (Mycoplasmas), and various Lactobacillales including Streptococcus. It is also missing, of course, from the Archaea, which also lack Nus factors. Members of this family from Micrococcus luteus, Mycobacterium tuberculosis, and related species have a related but highly variable long, highly charged insert near the amino end. Members of this family differ in the specificity of RNA binding.
ReferencesRN [1] RM PMID:16946247 RT Rho-dependent terminators and transcription termination. RA Ciampi MS RL Microbiology. 2006 Sep;152(Pt 9):2515-28. AL manual
Genome PropertyGenProp0812: rho-dependent termination (HMM)