HMM Summary Page: TIGR00786

AccessionTIGR00786
NamedctM
FunctionTRAP transporter, DctM subunit
Trusted Cutoff268.45
Domain Trusted Cutoff268.45
Noise Cutoff131.85
Domain Noise Cutoff131.85
Isology Typesubfamily
HMM Length405
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
Gene Ontology TermGO:0005887: integral to plasma membrane cellular_component
GO:0005887: integral to plasma membrane cellular_component
GO:0005887: integral to plasma membrane cellular_component
GO:0015556: C4-dicarboxylate transmembrane transporter activity molecular_function
GO:0015556: C4-dicarboxylate transmembrane transporter activity molecular_function
GO:0015556: C4-dicarboxylate transmembrane transporter activity molecular_function
GO:0015740: C4-dicarboxylate transport biological_process
GO:0015740: C4-dicarboxylate transport biological_process
GO:0015740: C4-dicarboxylate transport biological_process
GO:0031317: tripartite ATP-independent periplasmic transporter complex cellular_component
GO:0031317: tripartite ATP-independent periplasmic transporter complex cellular_component
GO:0031317: tripartite ATP-independent periplasmic transporter complex cellular_component
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus.
ReferencesA2 hmmalign SE Ipaulsen AL clustalw_manual
Genome PropertyGenProp0176: TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters (HMM)
GenProp0176: TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters (HMM)
GenProp0176: TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters (HMM)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (MANUAL)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (MANUAL)
GenProp0714: galactarate utilization via tartronate semi-aldehyde (MANUAL)