HMM Summary Page: TIGR00797

FunctionMATE efflux family protein
Trusted Cutoff147.40
Domain Trusted Cutoff147.40
Noise Cutoff123.20
Domain Noise Cutoff123.20
Isology Typesubfamily
HMM Length396
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0006855: drug transmembrane transport biological_process
GO:0015559: multidrug efflux pump activity molecular_function
GO:0016020: membrane cellular_component
GO:0042493: response to drug biological_process
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS.
ReferencesSE Ipaulsen AL clustalw_manual DR HAMAP; MF_00400; 33 of 34