| Accession | TIGR00829 |
| Name | FRU |
| Function | PTS system, Fru family, IIB component |
| Trusted Cutoff | 76.85 |
| Domain Trusted Cutoff | 76.85 |
| Noise Cutoff | 64.15 |
| Domain Noise Cutoff | 64.15 |
| Isology Type | subfamily_domain |
| EC Number | 2.7.1.69 |
| HMM Length | 85 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Carbohydrates, organic alcohols, and acids |
| Author | Loftus BJ |
| Entry Date | Jul 25 2000 6:19PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several PTS components of unknown specificities. The fructose components of this family phosphorylate fructose on the 1-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIB domain of the fructose PTS transporters. |
| References | SE ipaulsen
DR URL; http://www-biology.ucsd.edu/~msaier/transport/4_A_2.html |
| Genome Property | GenProp0119: PTS transport system (HMM) |
| | GenProp0693: fructose utilization as fructose-1,6-bisphosphate (HMM) |