|Function||cation transporter protein|
|Domain Trusted Cutoff||288.00|
|Domain Noise Cutoff||260.40|
|Mainrole Category||Transport and binding proteins|
|Subrole Category||Cations and iron carrying compounds|
|Author||Paulsen IT, Saier MH, Loftus BJ|
|Entry Date||Aug 11 2000 1:26PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||ATP-gated Cation Channel (ACC) Family (TC 1.A.7)
Members of the ACC family (also called P2X receptors) respond to ATP, a functional neurotransmitter released by exocytosis from many types of neurons.
These channels, which function at neuron-neuron and neuron-smooth muscle junctions, may play roles in the control of blood pressure and pain sensation. They may also function in lymphocyte and platelet
physiology. They are found only in animals.
ACC channels are probably hetero- or homomultimers and transport small monovalent cations (Me+). Some also transport Ca2+; a few also transport small metabolites.
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