| Accession | TIGR00877 |
| Name | purD |
| Function | phosphoribosylamine--glycine ligase |
| Gene Symbol | purD |
| Trusted Cutoff | 288.00 |
| Domain Trusted Cutoff | 288.00 |
| Noise Cutoff | 199.75 |
| Domain Noise Cutoff | 199.75 |
| Isology Type | equivalog_domain |
| EC Number | 6.3.4.13 |
| HMM Length | 425 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Purine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004637: phosphoribosylamine-glycine ligase activity molecular_function |
| | GO:0006189: 'de novo' IMP biosynthetic process biological_process |
| | GO:0009152: purine ribonucleotide biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Sep 11 2000 8:28AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Alternate name: glycinamide ribonucleotide synthetase (GARS).
This enzyme appears as a monofunctional protein in prokaryotes but as part of a larger, multidomain protein in eukaryotes. |
| References | DR EXPERIMENTAL; EGAD|7937|EC4005; Escherichia coli
DR ECOCYC; EG10792; purD
DR HAMAP; MF_00138; 94 of 95 |
| Genome Property | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
