HMM Summary Page: TIGR00877

AccessionTIGR00877
NamepurD
Functionphosphoribosylamine--glycine ligase
Gene SymbolpurD
Trusted Cutoff288.00
Domain Trusted Cutoff288.00
Noise Cutoff199.75
Domain Noise Cutoff199.75
Isology Typeequivalog_domain
EC Number6.3.4.13
HMM Length425
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0004637: phosphoribosylamine-glycine ligase activity molecular_function
GO:0006189: 'de novo' IMP biosynthetic process biological_process
GO:0009152: purine ribonucleotide biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 11 2000 8:28AM
Last ModifiedFeb 14 2011 3:27PM
CommentAlternate name: glycinamide ribonucleotide synthetase (GARS). This enzyme appears as a monofunctional protein in prokaryotes but as part of a larger, multidomain protein in eukaryotes.
ReferencesDR EXPERIMENTAL; EGAD|7937|EC4005; Escherichia coli DR ECOCYC; EG10792; purD DR HAMAP; MF_00138; 94 of 95
Genome PropertyGenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)