HMM Summary Page: TIGR00884

FunctionGMP synthase (glutamine-hydrolyzing), C-terminal domain
Gene SymbolguaA
Trusted Cutoff338.75
Domain Trusted Cutoff338.75
Noise Cutoff126.15
Domain Noise Cutoff126.15
Isology Typeequivalog_domain
EC Number6.3.5.2
HMM Length310
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0003922: GMP synthase (glutamine-hydrolyzing) activity molecular_function
GO:0009152: purine ribonucleotide biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 11 2000 2:53PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein of purine de novo biosynthesis is well-conserved. However, it appears to split into two separate polypeptide chains in most of the Archaea. This C-terminal region would be the larger subunit
ReferencesDR HAMAP; MF_00345; 24 of 26
Genome PropertyGenProp0696: xanthine utilization as a source of guanine-monophosphate (GMP) (HMM)
GenProp0697: guanine monophosphate (GMP) biosynthesis from inosine monophosphate (IMP) (HMM)