HMM Summary Page: TIGR00938

Functionhomoserine kinase
Gene SymbolthrB
Trusted Cutoff255.90
Domain Trusted Cutoff255.90
Noise Cutoff133.60
Domain Noise Cutoff133.60
Isology Typeequivalog
EC Number2.7.1.39
HMM Length307
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
Gene Ontology TermGO:0004413: homoserine kinase activity molecular_function
GO:0009088: threonine biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 18 2000 11:16AM
Last ModifiedFeb 14 2011 3:27PM
CommentHomoserine kinase is required in the biosynthesis of threonine from aspartate.The member of this family from Pseudomonas aeruginosa was shown by direct assay and complementation to act specifically as a homoserine kinase.
ReferencesRM 93086420 RT Isolation, organization and expression of the Pseudomonas aeruginosa threonine genes. RA Clepet C, Borne F, Krishnapillai V, Baird C, Patte JC, Cami B RL Mol Microbiol 1992 Nov;6(21):3109-19 DR HAMAP; MF_00301; 68 of 69
Genome PropertyGenProp0159: threonine biosynthesis from aspartate semialdehyde (HMM)