HMM Summary Page: TIGR00962

AccessionTIGR00962
NameatpA
FunctionATP synthase F1, alpha subunit
Gene SymbolatpA
Trusted Cutoff484.45
Domain Trusted Cutoff484.45
Noise Cutoff209.00
Domain Noise Cutoff209.00
Isology Typeequivalog
EC Number3.6.3.14
HMM Length503
Mainrole CategoryEnergy metabolism
Subrole CategoryATP-proton motive force interconversion
Gene Ontology TermGO:0000275: mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) cellular_component
GO:0015986: ATP synthesis coupled proton transport biological_process
GO:0045261: proton-transporting ATP synthase complex, catalytic core F(1) cellular_component
GO:0045262: plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) cellular_component
GO:0046933: hydrogen ion transporting ATP synthase activity, rotational mechanism molecular_function
AuthorDurkin S, Haft DH
Entry DateSep 28 2000 11:51AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe sequences of ATP synthase F1 alpha and beta subunits are related and both contain a nucleotide-binding site for ATP and ADP. They have a common amino terminal domain but vary at the C-terminus. The beta chain has catalytic activity, while the alpha chain is a regulatory subunit. The alpha-subunit contains a highly conserved adenine-specific noncatalytic nucleotide-binding domain. The conserved amino acid sequence is Gly-X-X-X-X-Gly-Lys. Proton translocating ATP synthase F1, alpha subunit is homologous to proton translocating ATP synthase archaeal/vacuolar(V1), B subunit.
ReferencesDR EXPERIMENTAL; EGAD|19577|20051; E. coli DR HAMAP; MF_01346; 698 of 715
Genome PropertyGenProp0128: F1/F0 ATPase (HMM)
GenProp0800: bacterial core gene set, 1 or more per genome (HMM)