Accession | TIGR00965 |
Name | dapD |
Function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase |
Gene Symbol | dapD |
Trusted Cutoff | 375.40 |
Domain Trusted Cutoff | 375.40 |
Noise Cutoff | 53.60 |
Domain Noise Cutoff | 53.60 |
Isology Type | equivalog |
EC Number | 2.3.1.117 |
HMM Length | 271 |
Mainrole Category | Amino acid biosynthesis |
Subrole Category | Aspartate family |
Gene Ontology Term | GO:0008666: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity molecular_function |
| GO:0009089: lysine biosynthetic process via diaminopimelate biological_process |
Author | Haft DH |
Entry Date | Sep 28 2000 2:53PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This enzyme is part of the diaminopimelate pathway of lysine biosynthesis.
Alternate name: tetrahydrodipicolinate N-succinyltransferase.
The closely related TabB protein of Pseudomonas syringae (pv. tabaci), SP|P31852|TABB_PSESZ, appears to act in the biosynthesis of tabtoxin rather than lysine. The trusted cutoff is set high enough to exclude this gene. Sequences below trusted also include a version of this enzyme which apparently utilize acetate rather than succinate (EC: 2.3.1.89). |
References | RN [1]
RM PMID:9294453
RT A possible role for acetylated intermediates in diaminopimelate and tabtoxinine-beta-lactam biosynthesis in Pseudomonas syringae pv. tabaci BR2.024.
RA Liu L, Shaw PD
RL J Bacteriol. 1997 Sep;179(18):5922-7.
DR HAMAP; MF_00811; 185 of 190 |
Genome Property | GenProp0786: lysine biosynthesis via diaminopimelate (DAP), succinylated branch (HMM) |