| Accession | TIGR01033 |
| Name | TIGR01033 |
| Function | DNA-binding regulatory protein, YebC/PmpR family |
| Trusted Cutoff | 208.75 |
| Domain Trusted Cutoff | 208.75 |
| Noise Cutoff | 139.65 |
| Domain Noise Cutoff | 139.65 |
| Isology Type | subfamily |
| HMM Length | 238 |
| Mainrole Category | Regulatory functions |
| Subrole Category | DNA interactions |
| Gene Ontology Term | GO:0003677: DNA binding molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0045449: regulation of transcription biological_process |
| Author | Haft DH, Ujwal ML |
| Entry Date | Nov 13 2000 4:19PM |
| Last Modified | May 27 2014 3:50PM |
| Comment | This model describes a minimally characterized protein family, restricted to bacteria excepting for some eukaryotic sequences that have possible transit peptides. YebC from E. coli is crystallized, and PA0964 from Pseudomonas aeruginosa has been shown to be a sequence-specific DNA-binding regulatory protein. In silico analysis suggests a role in Holliday junction resolution. |
| References | RN [1]
RM PMID:23046553
RT In silico identification of a multi-functional regulatory protein involved in Holliday junction resolution in bacteria.
RA Zhang Y, Lin J, Gao Y
RL BMC Syst Biol. 2012 Jul 16;6 Suppl 1:S20. doi: 10.1186/1752-0509-6-S1-S20.
RN [2]
RM PMID:18641136
RT The YebC family protein PA0964 negatively regulates the Pseudomonas aeruginosa quinolone signal system and pyocyanin production.
RA Liang H, Li L, Dong Z, Surette MG, Duan K
RL J Bacteriol. 2008 Sep;190(18):6217-27. Epub 2008 Jul 18.
DR COGS; COG0217
DR HAMAP; MF_00693; 487 of 518 |
