| Accession | TIGR01036 |
| Name | pyrD_sub2 |
| Function | dihydroorotate dehydrogenase (fumarate) |
| Gene Symbol | pyrD |
| Trusted Cutoff | 200.00 |
| Domain Trusted Cutoff | 200.00 |
| Noise Cutoff | 200.00 |
| Domain Noise Cutoff | 200.00 |
| Isology Type | equivalog |
| EC Number | 1.3.98.1 |
| HMM Length | 356 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Pyrimidine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004158: dihydroorotate oxidase activity molecular_function |
| | GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process |
| Author | Ujwal ML, Haft DH |
| Entry Date | Nov 15 2000 4:44PM |
| Last Modified | Feb 14 2012 12:30PM |
| Comment | This model describes enzyme protein dihydroorotate dehydrogenase exclusively for subfamily 2. It includes members from bacteria, yeast, plants etc.
The subfamilies 1 and 2 share extensive homology, particularly toward the C-terminus. This subfamily has a longer N-terminal region. |
| References | DR COGS; COG0167
DR HAMAP; MF_00225; 260 of 263 |
| Genome Property | GenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM) |