Accession | TIGR01042 |
Name | V-ATPase_V1_A |
Function | V-type ATPase, A subunit |
Trusted Cutoff | 779.90 |
Domain Trusted Cutoff | 779.90 |
Noise Cutoff | 776.60 |
Domain Noise Cutoff | 776.60 |
Isology Type | equivalog |
EC Number | 3.6.3.14 |
HMM Length | 591 |
Mainrole Category | Transport and binding proteins |
Subrole Category | Cations and iron carrying compounds |
Gene Ontology Term | GO:0008553: hydrogen-exporting ATPase activity, phosphorylative mechanism molecular_function |
| GO:0015991: ATP hydrolysis coupled proton transport biological_process |
| GO:0016471: vacuolar proton-transporting V-type ATPase complex cellular_component |
Author | Durkin S |
Entry Date | Nov 16 2000 4:08PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase. |
References | RN [1]
RM 99240666
RT Structure and Properties of the Vacuolar (H+)-ATPases.
RA Forgac M;
RL J Biol Chem 1999;274:12951-12954. |