Accession | TIGR01051 |
Name | topA_bact |
Function | DNA topoisomerase I |
Gene Symbol | topA |
Trusted Cutoff | 456.40 |
Domain Trusted Cutoff | 456.40 |
Noise Cutoff | 379.15 |
Domain Noise Cutoff | 379.15 |
Isology Type | equivalog |
EC Number | 5.99.1.2 |
HMM Length | 632 |
Mainrole Category | DNA metabolism |
Subrole Category | DNA replication, recombination, and repair |
Gene Ontology Term | GO:0003677: DNA binding molecular_function |
| GO:0003917: DNA topoisomerase type I activity molecular_function |
| GO:0005737: cytoplasm cellular_component |
| GO:0006260: DNA replication biological_process |
| GO:0006265: DNA topological change biological_process |
Author | Ujwal ML, Haft DH |
Entry Date | Nov 27 2000 1:17PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model describes DNA topoisomerase I among the members of bacteria. DNA topoisomerase I transiently cleaves one DNA strand and thus relaxes negatively supercoiled DNA during replication, transcription and recombination events. |