HMM Summary Page: TIGR01082

FunctionUDP-N-acetylmuramate--L-alanine ligase
Gene SymbolmurC
Trusted Cutoff335.10
Domain Trusted Cutoff335.10
Noise Cutoff292.80
Domain Noise Cutoff292.80
Isology Typeequivalog
EC Number6.3.2.8
HMM Length449
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of murein sacculus and peptidoglycan
Gene Ontology TermGO:0008763: UDP-N-acetylmuramate-L-alanine ligase activity molecular_function
GO:0009252: peptidoglycan biosynthetic process biological_process
AuthorHaft DH, Dodson RJ
Entry DateDec 19 2000 5:22PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by HMM TIGR01081.
ReferencesDR HAMAP; MF_00046; 480 of 487
Genome PropertyGenProp0158: peptidoglycan(murein) biosynthesis (HMM)