| Accession | TIGR01082 |
| Name | murC |
| Function | UDP-N-acetylmuramate--alanine ligase |
| Gene Symbol | murC |
| Trusted Cutoff | 335.10 |
| Domain Trusted Cutoff | 335.10 |
| Noise Cutoff | 292.80 |
| Domain Noise Cutoff | 292.80 |
| Isology Type | equivalog |
| EC Number | 6.3.2.8 |
| HMM Length | 449 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0008763: UDP-N-acetylmuramate-L-alanine ligase activity molecular_function |
| | GO:0009252: peptidoglycan biosynthetic process biological_process |
| Author | Haft DH, Dodson RJ |
| Entry Date | Dec 19 2000 5:22PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine.
A related protein,
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by HMM TIGR01081. |
| References |
DR HAMAP; MF_00046; 480 of 487 |
| Genome Property | GenProp0158: peptidoglycan(murein) biosynthesis (HMM) |
