HMM Summary Page: TIGR01090

Functionadenine phosphoribosyltransferase
Gene Symbolapt
Trusted Cutoff185.85
Domain Trusted Cutoff185.85
Noise Cutoff68.80
Domain Noise Cutoff68.80
Isology Typeequivalog
EC Number2.4.2.7
HMM Length169
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategorySalvage of nucleosides and nucleotides
Gene Ontology TermGO:0003999: adenine phosphoribosyltransferase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006166: purine ribonucleoside salvage biological_process
AuthorHaft DH
Entry DateDec 22 2000 10:00AM
Last ModifiedFeb 14 2011 3:27PM
CommentA phylogenetic analysis suggested omitting the bi-directional best hit homologs from the spirochetes from the seed for this HMM and making only tentative predictions of adenine phosphoribosyltransferase function for this lineage. The trusted cutoff score is made high for this reason. Most proteins scoring between the trusted and noise cutoffs are likely to act as adenine phosphotransferase.
References DR HAMAP; MF_00004; 405 of 474