HMM Summary Page: TIGR01127

Functionthreonine ammonia-lyase
Gene SymbolilvA
Trusted Cutoff378.75
Domain Trusted Cutoff378.75
Noise Cutoff336.90
Domain Noise Cutoff336.90
Isology Typeequivalog
EC Number4.3.1.19
HMM Length380
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryPyruvate family
Gene Ontology TermGO:0004794: L-threonine ammonia-lyase activity molecular_function
GO:0006549: isoleucine metabolic process biological_process
AuthorHaft DH
Entry DateJan 16 2001 11:42PM
Last ModifiedAug 12 2011 9:01AM
CommentA form of threonine dehydratase with two copies of the C-terminal domain Pfam:PF00585 is described by TIGR01124. This model describes a phylogenetically distinct form with a single copy of PF00585. This form branches with the catabolic threonine dehydratase of E. coli; many members are designated as catabolic for this reason. However, the catabolic form lacks any PF00585 domain. Many members of this model are found in species with other Ile biosynthetic enzymes.
Genome PropertyGenProp0162: isoleucine biosynthesis from threonine and pyruvate (HMM)