HMM Summary Page: TIGR01131

AccessionTIGR01131
NameATP_synt_6_or_A
FunctionATP synthase F0, A subunit
Gene SymbolatpB
Trusted Cutoff102.60
Domain Trusted Cutoff102.60
Noise Cutoff90.90
Domain Noise Cutoff90.90
Isology Typeequivalog
EC Number3.6.3.14
HMM Length227
Mainrole CategoryEnergy metabolism
Subrole CategoryATP-proton motive force interconversion
Gene Ontology TermGO:0000276: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) cellular_component
GO:0015986: ATP synthesis coupled proton transport biological_process
GO:0045263: proton-transporting ATP synthase complex, coupling factor F(o) cellular_component
GO:0045264: plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) cellular_component
GO:0046933: hydrogen ion transporting ATP synthase activity, rotational mechanism molecular_function
AuthorUjwal ML, Paulsen IT
Entry DateJan 24 2001 4:12PM
Last ModifiedFeb 14 2011 3:27PM
CommentBacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process.
References DR HAMAP; MF_01393; 78 of 81
Genome PropertyGenProp0128: F1/F0 ATPase (HMM)