| Accession | TIGR01190 |
| Name | ccmB |
| Function | heme exporter protein CcmB |
| Gene Symbol | ccmB |
| Trusted Cutoff | 156.20 |
| Domain Trusted Cutoff | 156.20 |
| Noise Cutoff | 29.50 |
| Domain Noise Cutoff | 29.50 |
| Isology Type | equivalog |
| HMM Length | 211 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0015232: heme transporter activity molecular_function |
| | GO:0015886: heme transport biological_process |
| Author | Ujwal ML, Haft DH, Paulsen IT |
| Entry Date | Mar 4 2001 11:00PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes the cyt c biogenesis protein encoded by ccmB in bacteria. Bacterial c-type cytochromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome C. |
| Genome Property | GenProp0678: c-type cytochrome biogenesis, system I (HMM) |
