HMM Summary Page: TIGR01220

Functionphosphomevalonate kinase
Trusted Cutoff165.70
Domain Trusted Cutoff165.70
Noise Cutoff70.35
Domain Noise Cutoff70.35
Isology Typeequivalog
EC Number2.7.4.2
HMM Length358
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryOther
Gene Ontology TermGO:0004631: phosphomevalonate kinase activity molecular_function
GO:0016126: sterol biosynthetic process biological_process
GO:0019287: isopentenyl diphosphate biosynthetic process, mevalonate pathway biological_process
AuthorHaft DH
Entry DateMay 3 2001 10:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme is part of the mevalonate pathway, one of two alternative pathways for the biosynthesis of IPP. In an example of nonorthologous gene displacement, two different types of phosphomevalonate kinase are found - the animal type and this ERG8 type. This model represents the low GC Gram-positive organism forms of the ERG8 type of phosphomevalonate kinase.
Genome PropertyGenProp0047: IPP biosynthesis via mevalonate (HMM)