| Accession | TIGR01254 |
| Name | sfuA |
| Function | ABC transporter periplasmic binding protein, thiB subfamily |
| Trusted Cutoff | 93.40 |
| Domain Trusted Cutoff | 93.40 |
| Noise Cutoff | 76.00 |
| Domain Noise Cutoff | 76.00 |
| Isology Type | subfamily |
| HMM Length | 306 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Other |
| Gene Ontology Term | GO:0009897: external side of plasma membrane cellular_component |
| | GO:0015619: thiamine pyrophosphate-transporting ATPase activity molecular_function |
| | GO:0015888: thiamine transport biological_process |
| | GO:0030288: outer membrane-bounded periplasmic space cellular_component |
| | GO:0030974: thiamine pyrophosphate transport biological_process |
| | GO:0030975: thiamine binding molecular_function |
| | GO:0030976: thiamine pyrophosphate binding molecular_function |
| | GO:0048502: thiamine-transporting ATPase activity molecular_function |
| | GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component |
| Author | Ujwal ML, Paulsen IT |
| Entry Date | May 22 2001 4:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The model describes thiamine ABC transporter, periplasmic protein in bacteria and archae. The protein belongs to the larger ABC transport system. It consists of at least three components: the thiamine binding periplasmic protein; an inner membrane permease; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). |
