HMM Summary Page: TIGR01264

Functiontyrosine aminotransferase
Gene SymbolTAT
Trusted Cutoff474.25
Domain Trusted Cutoff474.25
Noise Cutoff256.05
Domain Noise Cutoff256.05
Isology Typeequivalog
EC Number2.6.1.5
HMM Length403
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0004838: L-tyrosine:2-oxoglutarate aminotransferase activity molecular_function
GO:0006559: L-phenylalanine catabolic process biological_process
GO:0006572: tyrosine catabolic process biological_process
AuthorHaft DH
Entry DateJun 4 2001 11:37AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs.
Genome PropertyGenProp0139: degradation of tyrosine via homogentisate (HMM)