HMM Summary Page: TIGR01297

Functioncation diffusion facilitator family transporter
Trusted Cutoff82.35
Domain Trusted Cutoff82.35
Noise Cutoff73.35
Domain Noise Cutoff73.35
Isology Typesuperfamily
HMM Length285
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0006812: cation transport biological_process
GO:0008324: cation transmembrane transporter activity molecular_function
GO:0015562: efflux transmembrane transporter activity molecular_function
GO:0016020: membrane cellular_component
AuthorHaft DH, Paulsen IT, Saier MH
Entry DateJul 2 2001 10:58AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a broadly distributed family of transporters, a number of which have been shown to transport divalent cations of cobalt, cadmium and/or zinc. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence.
ReferencesDR URL; DR PFAM; PF01545; Cation_efflux RM 9075641 RT A novel family of ubiquitous heavy metal ion transport proteins. RA Paulsen IT, Saier MH Jr. RL J Membr Biol 1997 Mar 15;156(2):99-103 DR HAMAP; MF_01425; 30 of 31