HMM Summary Page: TIGR01323

Functionnitrile hydratase, alpha subunit
Gene SymbolnthA
Trusted Cutoff249.85
Domain Trusted Cutoff249.85
Noise Cutoff239.05
Domain Noise Cutoff239.05
Isology Typeequivalog
EC Number4.2.1.84
HMM Length189
Gene Ontology TermGO:0018822: nitrile hydratase activity molecular_function
GO:0050898: nitrile metabolic process biological_process
AuthorHaft DH
Entry DateAug 15 2001 12:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes both iron- and cobalt-containing nitrile hydratase alpha chains. It excludes the thiocyanate hydrolase gamma subunit of Thiobacillus thioparus, a sequence that appears to have evolved from within the family of nitrile hydratase alpha subunits but which differs by several indels and a more rapid accumulation of point mutations.
ReferencesDR EXPERIMENTAL; SP|P29378; Rhodococcus rhodochrous; cobalt-containing DR EXPERIMENTAL; SP:P97051; Pseudomonas putida; cobalt-containing DR EXPERIMENTAL; SP:P13448; Rhodococcus erythropolis; iron-containing DR EXCEPTION; GP|3142158; thiocyanate hydrolase gamma subunit; Thiobacillus thioparus
Genome PropertyGenProp0899: nitrile hydratase (HMM)