HMM Summary Page: TIGR01325

FunctionO-succinylhomoserine sulfhydrylase
Gene SymbolmetZ
Trusted Cutoff510.05
Domain Trusted Cutoff510.05
Noise Cutoff433.55
Domain Noise Cutoff433.55
Isology Typeequivalog
EC Number4.2.99.-
HMM Length380
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
Gene Ontology TermGO:0008652: cellular amino acid biosynthetic process biological_process
GO:0016835: carbon-oxygen lyase activity molecular_function
AuthorHaft DH
Entry DateAug 23 2001 12:12PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis.
ReferencesDR PROSITE; PDOC00677; Cys/Met metabolism enzymes pyridoxal-phosphate attachment site DR EXPERIMENTAL; OMNI|NTL03PA03107; Pseudomonas aeruginosa DR EXPERIMENTAL; GP|4191271; Rhizobium etli
Genome PropertyGenProp0161: methionine biosynthesis from homoserine (HMM)