| Accession | TIGR01326 |
| Name | OAH_OAS_sulfhy |
| Function | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase |
| Trusted Cutoff | 495.10 |
| Domain Trusted Cutoff | 495.10 |
| Noise Cutoff | 483.05 |
| Domain Noise Cutoff | 483.05 |
| Isology Type | subfamily |
| HMM Length | 418 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aspartate family |
| Gene Ontology Term | GO:0003961: O-acetylhomoserine aminocarboxypropyltransferase activity molecular_function |
| | GO:0004124: cysteine synthase activity molecular_function |
| | GO:0009086: methionine biosynthetic process biological_process |
| | GO:0016765: transferase activity, transferring alkyl or aryl (other than methyl) groups molecular_function |
| | GO:0019344: cysteine biosynthetic process biological_process |
| | GO:0019413: acetate biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Aug 23 2001 12:51PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This HMM is designated subfamily because it may or may not have both activities. |
| References | DR PROSITE; PDOC00677; Cys/Met metabolism enzymes pyridoxal-phosphate attachment site |
| Genome Property | GenProp0161: methionine biosynthesis from homoserine (HMM) |
