| Accession | TIGR01347 |
| Name | sucB |
| Function | dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex |
| Gene Symbol | sucB |
| Trusted Cutoff | 378.65 |
| Domain Trusted Cutoff | 378.65 |
| Noise Cutoff | 329.90 |
| Domain Noise Cutoff | 329.90 |
| Isology Type | equivalog |
| EC Number | 2.3.1.61 |
| HMM Length | 404 |
| Mainrole Category | Energy metabolism |
| Subrole Category | TCA cycle |
| Gene Ontology Term | GO:0004149: dihydrolipoyllysine-residue succinyltransferase activity molecular_function |
| | GO:0006099: tricarboxylic acid cycle biological_process |
| | GO:0006554: lysine catabolic process biological_process |
| | GO:0045252: oxoglutarate dehydrogenase complex cellular_component |
| Author | Haft DH |
| Entry Date | Sep 21 2001 10:55AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component,
dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. |
| References | DR PF00198; 2-oxoacid_dh
DR PF00364; biotin_lipoyl |
| Genome Property | GenProp0630: 2-oxoglutarate dehydrogenase system (HMM) |
