Accession | TIGR01347 |
Name | sucB |
Function | dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex |
Gene Symbol | sucB |
Trusted Cutoff | 378.65 |
Domain Trusted Cutoff | 378.65 |
Noise Cutoff | 329.90 |
Domain Noise Cutoff | 329.90 |
Isology Type | equivalog |
EC Number | 2.3.1.61 |
HMM Length | 404 |
Mainrole Category | Energy metabolism |
Subrole Category | TCA cycle |
Gene Ontology Term | GO:0004149: dihydrolipoyllysine-residue succinyltransferase activity molecular_function |
| GO:0006099: tricarboxylic acid cycle biological_process |
| GO:0006554: lysine catabolic process biological_process |
| GO:0045252: oxoglutarate dehydrogenase complex cellular_component |
Author | Haft DH |
Entry Date | Sep 21 2001 10:55AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component,
dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. |
References | DR PF00198; 2-oxoacid_dh
DR PF00364; biotin_lipoyl |
Genome Property | GenProp0630: 2-oxoglutarate dehydrogenase system (HMM) |