HMM Summary Page: TIGR01367

Functionorotate phosphoribosyltransferase
Gene SymbolpyrE
Trusted Cutoff150.25
Domain Trusted Cutoff150.25
Noise Cutoff107.00
Domain Noise Cutoff107.00
Isology Typeequivalog
EC Number2.4.2.10
HMM Length187
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPyrimidine ribonucleotide biosynthesis
Gene Ontology TermGO:0004588: orotate phosphoribosyltransferase activity molecular_function
GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process
AuthorHaft DH
Entry DateOct 26 2001 4:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a distinct clade of orotate phosphoribosyltransferases. Members include the experimentally determined example from Thermus aquaticus and additional examples from Caulobacter crescentus, Helicobacter pylori, Mesorhizobium loti, and related species.
ReferencesDR EXPERIMENTAL; EGAD|42983; Thermus aquaticus DR HAMAP; MF_01208; 47 of 300
Genome PropertyGenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM)