| Accession | TIGR01368 |
| Name | CPSaseIIsmall |
| Function | carbamoyl-phosphate synthase, small subunit |
| Gene Symbol | carA |
| Trusted Cutoff | 307.35 |
| Domain Trusted Cutoff | 307.35 |
| Noise Cutoff | 133.55 |
| Domain Noise Cutoff | 133.55 |
| Isology Type | equivalog_domain |
| EC Number | 6.3.5.5 |
| HMM Length | 361 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Pyrimidine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004088: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity molecular_function |
| | GO:0005951: carbamoyl-phosphate synthase complex cellular_component |
| | GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Oct 29 2001 11:17AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents the whole of the small chain of the glutamine-dependent form (EC 6.3.5.5) of carbamoyl phosphate synthase, CPSase II. The C-terminal domain has glutamine amidotransferase activity. Note that the sequence from the mammalian urea cycle form has lost the active site Cys, resulting in an ammonia-dependent form, CPSase I (EC 6.3.4.16). CPSases of pyrimidine biosynthesis, arginine biosynthesis, and the urea cycle may be encoded by one or by several genes, depending on the species. |
| References | DR EXCEPTION; SP|P31327; EC 6.3.4.16 (no GATase activity)
DR HAMAP; MF_01209; 131 of 131 |
| Genome Property | GenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM) |
