| Accession | TIGR01380 |
| Name | glut_syn |
| Function | glutathione synthase |
| Gene Symbol | gshB |
| Trusted Cutoff | 299.05 |
| Domain Trusted Cutoff | 299.05 |
| Noise Cutoff | 112.05 |
| Domain Noise Cutoff | 112.05 |
| Isology Type | equivalog |
| EC Number | 6.3.2.3 |
| HMM Length | 312 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Glutathione and analogs |
| Gene Ontology Term | GO:0004363: glutathione synthase activity molecular_function |
| | GO:0006750: glutathione biosynthetic process biological_process |
| Author | Beanan M |
| Entry Date | Nov 16 2001 3:48PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model was built using glutathione synthetases found in Gram-negative bacteria. This gene does not appear to be present in genomes of Gram-positive bacteria. Glutathione synthetase has an ATP-binding domain in the COOH terminus and catalyzes the second step in the glutathione biosynthesis pathway: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. Glutathione is a tripeptide that functions as a reductant in many cellular reactions. |
| References |
DR HAMAP; MF_00162; 51 of 51 |
| Genome Property | GenProp0030: glutathione biosynthesis (HMM) |
