| Accession | TIGR01414 |
| Name | autotrans_barl |
| Function | outer membrane autotransporter barrel domain |
| Trusted Cutoff | 16.00 |
| Domain Trusted Cutoff | 16.00 |
| Noise Cutoff | 15.90 |
| Domain Noise Cutoff | 15.90 |
| Isology Type | domain |
| HMM Length | 432 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0009405: pathogenesis biological_process |
| | GO:0015474: autotransporter activity molecular_function |
| | GO:0019867: outer membrane cellular_component |
| | GO:0046819: protein secretion by the type V secretion system biological_process |
| Author | Haft DH |
| Entry Date | Jan 7 2002 5:27PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. |
| Genome Property | GenProp1074: type V secretion (HMM) |
