HMM Summary Page: TIGR01414

Functionouter membrane autotransporter barrel domain
Trusted Cutoff16.00
Domain Trusted Cutoff16.00
Noise Cutoff15.90
Domain Noise Cutoff15.90
Isology Typedomain
HMM Length432
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0009405: pathogenesis biological_process
GO:0015474: autotransporter activity molecular_function
GO:0019867: outer membrane cellular_component
GO:0046819: protein secretion by the type V secretion system biological_process
AuthorHaft DH
Entry DateJan 7 2002 5:27PM
Last ModifiedFeb 14 2011 3:27PM
CommentA number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus.
Genome PropertyGenProp1074: type V secretion (HMM)