| Accession | TIGR01436 |
| Name | glu_cys_lig_pln |
| Function | glutamate--cysteine ligase |
| Trusted Cutoff | 463.15 |
| Domain Trusted Cutoff | 463.15 |
| Noise Cutoff | 90.55 |
| Domain Noise Cutoff | 90.55 |
| Isology Type | equivalog |
| EC Number | 6.3.2.2 |
| HMM Length | 446 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Glutathione and analogs |
| Gene Ontology Term | GO:0004357: glutamate-cysteine ligase activity molecular_function |
| | GO:0006750: glutathione biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Feb 5 2002 3:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents one of two highly dissimilar forms of glutamate--cysteine ligase (gamma-glutamylcysteine synthetase), an enzyme of glutathione biosynthesis. The other type is modeled by TIGR01434. This type is found in plants (with a probable transit peptide), root nodule and other bacteria, but not E. coli and closely related species. |
| Genome Property | GenProp0030: glutathione biosynthesis (HMM) |