|Function||transcriptional regulator, AbrB family|
|Domain Trusted Cutoff||28.30|
|Domain Noise Cutoff||26.15|
|Mainrole Category||Regulatory functions|
|Subrole Category||DNA interactions|
|Gene Ontology Term||GO:0003700: sequence-specific DNA binding transcription factor activity molecular_function|
| ||GO:0006355: regulation of transcription, DNA-dependent biological_process|
|Entry Date||Feb 7 2002 2:41PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609.|
RT Novel DNA binding domain and genetic regulation model of Bacillus subtilis transition state regulator abrB.
RA Vaughn JL, Feher V, Naylor S, Strauch MA, Cavanagh J.
RL Nat Struct Biol 2000 Dec;7(12):1139-46|
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