HMM Summary Page: TIGR01466

Functionprecorrin-3B C17-methyltransferase
Gene SymbolcobJ
Trusted Cutoff246.35
Domain Trusted Cutoff246.35
Noise Cutoff103.80
Domain Noise Cutoff103.80
Isology Typeequivalog_domain
EC Number2.1.1.131
HMM Length239
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryHeme, porphyrin, and cobalamin
Gene Ontology TermGO:0009236: cobalamin biosynthetic process biological_process
GO:0030789: precorrin-3B C17-methyltransferase activity molecular_function
AuthorHaft DH
Entry DateMar 12 2002 5:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents precorrin-3B C17-methyltransferase, one of two methyltransferases commonly referred to as precorrin-3 methylase (the other is precorrin-4 C11-methyltransferase, EC This enzyme participates in the pathway toward the biosynthesis of cobalamin and related products. Members of this family may appear as fusion proteins with other enzymes of cobalamin biosynthesis.
Genome PropertyGenProp0113: cobyrinic acid diamide biosynthesis, aerobic pathway (HMM)
GenProp0275: cobyrinic acid diamide biosynthesis, anaerobic pathway (HMM)