| Accession | TIGR01520 |
| Name | FruBisAldo_II_A |
| Function | fructose-bisphosphate aldolase, class II |
| Gene Symbol | fbaA |
| Trusted Cutoff | 347.70 |
| Domain Trusted Cutoff | 347.70 |
| Noise Cutoff | 206.25 |
| Domain Noise Cutoff | 206.25 |
| Isology Type | equivalog |
| EC Number | 4.1.2.13 |
| HMM Length | 357 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Glycolysis/gluconeogenesis |
| Gene Ontology Term | GO:0004332: fructose-bisphosphate aldolase activity molecular_function |
| | GO:0006096: glycolysis biological_process |
| Author | Haft DH |
| Entry Date | May 22 2002 3:25PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA).
This HMM represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. |
| References | DR EXPERIMENTAL; SP|P14540; Saccharomyces cerevisiae
DR EXPERIMENTAL; SP|P19537; Corynebacterium glutamicum
DR EXPERIMENTAL; SP|P11604; Escherichia coli |
| Genome Property | GenProp0120: pentose phosphate cycle (HMM) |
| | GenProp0691: glycolysis (HMM) |
