| Accession | TIGR01524 |
| Name | ATPase-IIIB_Mg |
| Function | magnesium-translocating P-type ATPase |
| Gene Symbol | mgtA |
| Trusted Cutoff | 610.75 |
| Domain Trusted Cutoff | 610.75 |
| Noise Cutoff | 563.35 |
| Domain Noise Cutoff | 563.35 |
| Isology Type | equivalog |
| EC Number | 3.6.3.2 |
| HMM Length | 867 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Cations and iron carrying compounds |
| Gene Ontology Term | GO:0015444: magnesium-importing ATPase activity molecular_function |
| | GO:0015693: magnesium ion transport biological_process |
| Author | Selengut J |
| Entry Date | May 24 2002 12:22PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes the magnesium translocating P-type ATPase found in a limited number of bacterial species and best described in Salmonella typhimurium, which contains two isoforms [1]. These transporters are active in low external Mg2+ concentrations and pump the ion into the cytoplasm.
The magnesium ATPases have been classified as type IIIB by a phylogenetic analysis [2]. |
| References | RN [1]
RM PMID: 1328179
RT MgtA and MgtB: prokaryotic P-type ATPases that mediate Mg2+ influx.
RA Maguire ME.
RL J Bioenerg Biomembr 1992 Jun;24(3):319-28
RN [2]
RM PMID:9419228
RT Evolution of Substrate Specificities in the P-type ATPase Superfamily.
RA Axelsen KB, Palmgren, MG.
RL J Mol Evol. 1998 Jan; 46(1): 84-101. |
