| Accession | TIGR01529 |
| Name | argR_whole |
| Function | arginine repressor |
| Gene Symbol | argR |
| Trusted Cutoff | 130.45 |
| Domain Trusted Cutoff | 130.45 |
| Noise Cutoff | 67.20 |
| Domain Noise Cutoff | 67.20 |
| Isology Type | equivalog |
| HMM Length | 146 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Glutamate family |
| Gene Ontology Term | GO:0006525: arginine metabolic process biological_process |
| | GO:0016564: transcription repressor activity molecular_function |
| Author | Haft DH |
| Entry Date | Jun 4 2002 3:14PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM includes most members of the arginine-responsive transcriptional regulator family ArgR. This hexameric protein binds DNA at its amino end to repress arginine biosyntheis or activate arginine catabolism. Some species have several ArgR paralogs. In a neighbor-joining tree, some of these paralogous sequences show long branches and differ significantly in an otherwise well-conserved C-terminal region motif GT[VIL][AC]GDDT. These paralogs are excluded from the seed and score in the gray zone of this model, between trusted and noise cutoffs. |
| References |
DR HAMAP; MF_00173; 169 of 192 |
