|Function||glyceraldehyde-3-phosphate dehydrogenase, type II|
|Domain Trusted Cutoff||232.90|
|Domain Noise Cutoff||56.25|
|Entry Date||Jun 12 2002 11:36AM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This HMM describes the type II glyceraldehyde-3-phosphate dehydrogenases which are limited to archaea. These enzymes catalyze the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. In archaea, either NAD or NADP may be utilized as the cofactor.
The class I GAPDH's from bacteria and eukaryotes are covered by TIGR01534.
All of the members of the seed are characterized. See, for instance . This model is very solid, there are no species falling between trusted and noise at this time. The closest relatives scoring in the noise are the class I GAPDH's.|
RM PMID: 2165475
RT Glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaebacterium Pyrococcus woesei: characterization of the enzyme, cloning and sequencing of the gene, and expression in Escherichia coli.
RA Zwickl P, Fabry S, Bogedain C, Haas A, Hensel R.
RL J Bacteriol 1990 Aug;172(8):4329-38.
DR HAMAP; MF_00559; 43 of 43|
|Genome Property||GenProp0691: glycolysis (HMM)|
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