| Accession | TIGR01556 |
| Name | rhamnosyltran |
| Function | rhamnosyltransferase |
| Trusted Cutoff | 200.55 |
| Domain Trusted Cutoff | 200.55 |
| Noise Cutoff | 191.50 |
| Domain Noise Cutoff | 191.50 |
| Isology Type | subfamily |
| EC Number | 2.4.1.- |
| HMM Length | 281 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
| Gene Ontology Term | GO:0009247: glycolipid biosynthetic process biological_process |
| | GO:0016757: transferase activity, transferring glycosyl groups molecular_function |
| Author | Brinkac L |
| Entry Date | Jun 17 2002 3:17PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM subfamily is comprised of gamma proteobacteria whose proteins function as L-rhamnosyltransferases in the synthesis of their respective surface polysaccharides.
Rhamnolipids are glycolipids containing mono- or di- L-rhamnose molecules. Rhamnolipid synthesis occurs by sequential glycosyltransferase reactions involving two distinct rhamnosyltransferase enzymes. In P.aeruginosa, the synthesis of mono-rhamnolipids is catalyzed by rhamnosyltransferase 1, and proceeds by a glycosyltransfer reaction catalyzed by rhamnosyltransferase 2 to yield di-rhamnolipids [1]. |
| References | RN [1]
RM 11359576
RT Cloning and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible for di-rhamnolipid biosynthesis.
RA Rahim R, Ochsner UA, Olvera C, Graninger M, Messner P, Lam JS, Soberon-Chavez G.
RL Mol Microbiol. 2001 May;40(3):708-18.
DR PFAM; PF00535; Glycosyl transferase
DR EXPERIMENTAL; OMNI|NTL03PA01131; Pseudomonas aeruginosa; Cloning and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible for di-rhamnolipid biosynthesis. |
| Genome Property | GenProp1051: O10(Ec) antigen biosynthesis (HMM-CLUST) |
