Accession | TIGR01556 |
Name | rhamnosyltran |
Function | rhamnosyltransferase |
Trusted Cutoff | 200.55 |
Domain Trusted Cutoff | 200.55 |
Noise Cutoff | 191.50 |
Domain Noise Cutoff | 191.50 |
Isology Type | subfamily |
EC Number | 2.4.1.- |
HMM Length | 281 |
Mainrole Category | Cell envelope |
Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
Gene Ontology Term | GO:0009247: glycolipid biosynthetic process biological_process |
| GO:0016757: transferase activity, transferring glycosyl groups molecular_function |
Author | Brinkac L |
Entry Date | Jun 17 2002 3:17PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM subfamily is comprised of gamma proteobacteria whose proteins function as L-rhamnosyltransferases in the synthesis of their respective surface polysaccharides.
Rhamnolipids are glycolipids containing mono- or di- L-rhamnose molecules. Rhamnolipid synthesis occurs by sequential glycosyltransferase reactions involving two distinct rhamnosyltransferase enzymes. In P.aeruginosa, the synthesis of mono-rhamnolipids is catalyzed by rhamnosyltransferase 1, and proceeds by a glycosyltransfer reaction catalyzed by rhamnosyltransferase 2 to yield di-rhamnolipids [1]. |
References | RN [1]
RM 11359576
RT Cloning and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible for di-rhamnolipid biosynthesis.
RA Rahim R, Ochsner UA, Olvera C, Graninger M, Messner P, Lam JS, Soberon-Chavez G.
RL Mol Microbiol. 2001 May;40(3):708-18.
DR PFAM; PF00535; Glycosyl transferase
DR EXPERIMENTAL; OMNI|NTL03PA01131; Pseudomonas aeruginosa; Cloning and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible for di-rhamnolipid biosynthesis. |
Genome Property | GenProp1051: O10(Ec) antigen biosynthesis (HMM-CLUST) |