Accession | TIGR01581 |
Name | Mo_ABC_porter |
Function | NifC-like ABC-type porter |
Trusted Cutoff | 210.30 |
Domain Trusted Cutoff | 210.30 |
Noise Cutoff | 202.60 |
Domain Noise Cutoff | 202.60 |
Isology Type | hypoth_equivalog |
HMM Length | 225 |
Gene Ontology Term | GO:0006810: transport biological_process |
| GO:0042626: ATPase activity, coupled to transmembrane movement of substances molecular_function |
| GO:0043190: ATP-binding cassette (ABC) transporter complex cellular_component |
Author | Selengut J |
Entry Date | Jul 10 2002 9:34AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way.
Included in this group is a gene designated NifC in Clostridium pasturianum [1]. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity. |
References | RN [1]
RM PMID: 2194453
RT A nitrogen-fixation gene (nifC) in Clostridium pasteurianum with sequence similarity to chlJ of Escherichia coli.
RA Wang SZ, Chen JS, Johnson JL.
RL Biochem Biophys Res Commun. 1990 Jun 29;169(3):1122-8. |