HMM Summary Page: TIGR01598

Functionholin, phage phi LC3 family
Trusted Cutoff39.70
Domain Trusted Cutoff39.70
Noise Cutoff26.80
Domain Noise Cutoff26.80
Isology Typeequivalog
HMM Length79
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryProphage functions
AuthorHaft DH, Fouts DE
Entry DateJul 24 2002 11:04AM
Last ModifiedFeb 14 2011 3:27PM
CommentPhage proteins for bacterial lysis typically include a membrane-disrupting protein, or holin, and one or more cell wall degrading enzymes that reach the cell wall because of holin action. Holins are found in a large number of mutually non-homologous families.
ReferencesDR EXPERIMENTAL; GP|530797; phage phi LC3 RM 7922887 RT Cloning, molecular characterization, and expression of the genes encoding the lytic functions of lactococcal bacteriophage phi LC3: a dual lysis system of modular design. RA Birkeland NK. RL Can J Microbiol 1994 Aug;40(8):658-65
Genome PropertyGenProp0208: phage: major features (HMM)