HMM Summary Page: TIGR01774
| Accession | TIGR01774 |
| Name | PFL2-3 |
| Function | glycyl radical enzyme, PFL2/glycerol dehydratase family |
| Trusted Cutoff | 678.20 |
| Domain Trusted Cutoff | 678.20 |
| Noise Cutoff | 464.45 |
| Domain Noise Cutoff | 464.45 |
| Isology Type | subfamily |
| HMM Length | 786 |
| Author | Haft DH, Selengut J |
| Entry Date | Dec 20 2002 3:22PM |
| Last Modified | Aug 31 2011 2:41PM |
| Comment | This family previously was designated pyruvate formate-lyase, but it now appears that members include the B12-independent glycerol dehydratase. Therefore, the functional definition of the family is being broadened. This family includes the PflF and PflD proteins of E. coli, described as isoforms of pyruvate-formate lyase found in a limited number additional species. PFL catalyzes the reaction pyruvate + CoA -> acetyl-CoA + formate, which is a step in the fermentation of glucose. |
| Genome Property | GenProp0943: pyruvate formate-lyase system (HMM) |