HMM Summary Page: TIGR01814

AccessionTIGR01814
Namekynureninase
Functionkynureninase
Gene SymbolkynU
Trusted Cutoff246.40
Domain Trusted Cutoff246.40
Noise Cutoff111.75
Domain Noise Cutoff111.75
Isology Typeequivalog
EC Number3.7.1.3
HMM Length400
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0019441: tryptophan catabolic process to kynurenine biological_process
GO:0019441: tryptophan catabolic process to kynurenine biological_process
GO:0019441: tryptophan catabolic process to kynurenine biological_process
GO:0030429: kynureninase activity molecular_function
GO:0030429: kynureninase activity molecular_function
GO:0030429: kynureninase activity molecular_function
AuthorHaft DH
Entry DateFeb 3 2003 4:53PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes kynureninase, a pyridoxal-phosphate enzyme. Kynurinine is a Trp breakdown product and a precursor for NAD. In Chlamydia psittaci, an obligate intracellular pathogen, kynureninase makes anthranilate, a Trp precursor, from kynurenine. This counters the tryptophan hydrolysis that occurs in the host cell in response to the pathogen.
Genome PropertyGenProp0659: tryptophan degradation to anthranilate (HMM)
GenProp0659: tryptophan degradation to anthranilate (HMM)
GenProp0659: tryptophan degradation to anthranilate (HMM)