HMM Summary Page: TIGR01814
Accession | TIGR01814 |
Name | kynureninase |
Function | kynureninase |
Gene Symbol | kynU |
Trusted Cutoff | 246.40 |
Domain Trusted Cutoff | 246.40 |
Noise Cutoff | 111.75 |
Domain Noise Cutoff | 111.75 |
Isology Type | equivalog |
EC Number | 3.7.1.3 |
HMM Length | 400 |
Mainrole Category | Energy metabolism |
Subrole Category | Amino acids and amines |
Gene Ontology Term | GO:0019441: tryptophan catabolic process to kynurenine biological_process |
GO:0030429: kynureninase activity molecular_function | |
Author | Haft DH |
Entry Date | Feb 3 2003 4:53PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes kynureninase, a pyridoxal-phosphate enzyme. Kynurinine is a Trp breakdown product and a precursor for NAD. In Chlamydia psittaci, an obligate intracellular pathogen, kynureninase makes anthranilate, a Trp precursor, from kynurenine. This counters the tryptophan hydrolysis that occurs in the host cell in response to the pathogen. |
Genome Property | GenProp0659: tryptophan degradation to anthranilate (HMM) |