HMM Summary Page: TIGR01814
| Accession | TIGR01814 |
| Name | kynureninase |
| Function | kynureninase |
| Gene Symbol | kynU |
| Trusted Cutoff | 246.40 |
| Domain Trusted Cutoff | 246.40 |
| Noise Cutoff | 111.75 |
| Domain Noise Cutoff | 111.75 |
| Isology Type | equivalog |
| EC Number | 3.7.1.3 |
| HMM Length | 400 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Amino acids and amines |
| Gene Ontology Term | GO:0019441: tryptophan catabolic process to kynurenine biological_process |
| GO:0030429: kynureninase activity molecular_function | |
| Author | Haft DH |
| Entry Date | Feb 3 2003 4:53PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes kynureninase, a pyridoxal-phosphate enzyme. Kynurinine is a Trp breakdown product and a precursor for NAD. In Chlamydia psittaci, an obligate intracellular pathogen, kynureninase makes anthranilate, a Trp precursor, from kynurenine. This counters the tryptophan hydrolysis that occurs in the host cell in response to the pathogen. |
| Genome Property | GenProp0659: tryptophan degradation to anthranilate (HMM) |