Accession | TIGR01821 |
Name | 5aminolev_synth |
Function | 5-aminolevulinic acid synthase |
Gene Symbol | hemA |
Trusted Cutoff | 338.55 |
Domain Trusted Cutoff | 338.55 |
Noise Cutoff | 334.75 |
Domain Noise Cutoff | 334.75 |
Isology Type | equivalog_domain |
EC Number | 2.3.1.37 |
HMM Length | 402 |
Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
Subrole Category | Heme, porphyrin, and cobalamin |
Gene Ontology Term | GO:0003870: 5-aminolevulinate synthase activity molecular_function |
| GO:0006783: heme biosynthetic process biological_process |
Author | Haft DH |
Entry Date | Feb 19 2003 12:41AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM represents 5-aminolevulinic acid synthase, an enzyme for one of two routes to the heme precursor 5-aminolevulinate. The protein is a pyridoxal phosphate-dependent enzyme related to 2-amino-3-ketobutyrate CoA tranferase and 8-amino-7-oxononanoate synthase. This enzyme appears restricted to the alpha Proteobacteria and mitochondrial derivatives. |
Genome Property | GenProp0223: 5-aminolevulinate biosynthesis from succinyl-CoA and glycine (HMM) |